What’s your hardware? Mainly what’s your display specifications, what desktop are you using, and what GPU
Sorry, updated my post
I experience this same issue (as OP, I’m pretty sure some of the other posts are for completely different issues) fairly frequently as well on KDE - it happens often when just web browsing or such, not just in games. Nothing in the System Monitor seems unusual (CPU or RAM usage) when it happens.
Specifically, I am running bazzite-asus-nvidia-open on an ASUS Zephyrus G14 GA403.
I have only started using Bazzite on my machine since the Bazzite 41 release, and it’s had this issue the entire time I’ve used it.